WebMay 18, 2010 · Interacts with NRP1 and SEMA4A (By similarity). Interacts with SH3BP1; they dissociate upon SEMA3E binding to PLXND1 allowing SH3BP1 to transduce downstream … WebSEMA4A involved in several pathways and played different roles in them. We selected most pathways SEMA4A participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in …
SEMA4A - Semaphorin-4A - Function
WebSEMA4D. SEMA4D is a membrane-bound semaphorin that is proteolytically cleaved to bind PLXNB1 in combination with MET tyrosine kinase receptor (Conrotto et al., 2005 ). These … WebOct 17, 2016 · In sum, our work identifies PlexinD1 as a novel transcriptional target induced by Notch signaling, and reveals its role promoting prostate cancer cell migration and downregulating E-cadherin levels in Slug-dependent manner. Collectively, these findings suggest that Notch-PlexinD1 signaling axis may be targeted to impair prostate cancer cell ... bohr postulates class 9
Human Plexin D1 Antibody AF4160: R&D Systems
WebMay 18, 2024 · SEMA3E appears to act primarily through PLXND1 in blood vessels. Alkaline phosphatase‐tagged SEMA3E (AP‐SEMA3E) bound to COS cells expressing PLXND1, but … WebSemaphorins comprise a large family of ligands that regulate key cellular functions through their receptors, plexins. In this study, we show that the transmembrane semaphorin 4A (Sema4A) can also... WebCell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of … bohrprisma