Phospho irf1
WebPhospho-IRF-7 (Ser471/472) Antibody detects transfected levels of IRF-7 when phosphorylated at Ser471 and 472. Species Reactivity: Human Source / Purification … WebIRF1 is an important regulatory factor in the protection against vessel wall damage. Mice deficient in IRF1 were highly susceptible to neointima formation after vessel injury. IRF1 …
Phospho irf1
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WebMar 11, 2024 · IRF1 is phosphorylated by GSK3β. ( A) Sequence conservation of the putative GSK3β phospho-target sequence in different species. The phosphorylated T180 and the … WebOct 29, 2015 · IRF1 is a critical transcription factor for iNOS induction and is antagonized by IRF2. In the stimulated macrophages, IRF1 accumulated in the nucleus without degradation by 5AZ treatment. In...
WebIHC image of FGFR1 (phospho Y654) staining in Human breast adenocarcinoma formalin fixed paraffin embedded tissue section, performed on a Leica Bond™ system using the … Web(C) GST–IRF-1 (100 ng) was immobilized on a microtitre plate and incubated with a titration (0–100 ng) of MDM2. Protein binding was detected using an anti-MDM2 mAb and the …
Web丁香通为您提供优黑素检测试剂盒进口试剂商品详情介绍:价格:询价,货号:ys-e92671,品牌:研生,产地:进口,供应商:上海研生,详见丁香通优黑素检测试剂盒进口试剂商品详情页; WebMar 11, 2024 · IRF1 (Interferon Regulatory Factor-1) is the prototype of the IRF family of DNA binding transcription factors. IRF1 protein expression is regulated by transient up-regulation in response to...
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WebMar 29, 2024 · IRF1 and IRF2 also appear to be important in regulating DC subset development— Irf −/− mice show a loss of splenic and epidermal DCs (due to augmented type I IFN signaling) ( 109, 110) whereas Irf1−/− exhibit an increase in pDCs and a decrease in CD8 + DCs in mice, along with an increase of IL-10 and TGF-β ( 111 ). family crisis services oxford msWebGet better batch-to-batch reproducibility with a recombinant antibody. Anti-IRE1 (phospho S724) antibody [EPR5253] (ab124945) Research with confidence – consistent and reproducible results with every batch. Long-term and scalable supply – powered by recombinant technology for fast production. family crisis services kansasWebApr 19, 2024 · Mutation of Tyr613 on IL-27Rα decreased IL-27-induced STAT1 phosphorylation by 80% but had limited effect on STAT3 phosphorgylation. Strong receptor/STAT coupling by IL-27 initiated a unique gene expression program, which required sustained STAT1 phosphorylation and IRF1 expression and was enriched in classical … cook hearing austintxWebBackground: Antiviral innate immunity depends on the combination of parallel pathways triggered by virus detecting proteins in the Toll-like receptor (TLR) family and RNA helicases, such as Rig-I (retinoic acid-inducible gene I) and MDA-5 (melanoma differentiation-associated antigen 5), which promote the transcription of type I interferons (IFN) and … family crisis services of northwest msWebPhospho-IRF7 (Ser437/438) IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to ... cook hearing cedar park txWebAug 1, 2024 · A and B: Western blot image of IRF1, phospho-Akt, total Akt, and β-Actin in IRF1-FLAG overexpressed HEK293T (A) or Calu3 (B) cells treated with insulin (100 nM) at the indicated time points. C: Western blot image of IRF1 and β-Actin in HEK293T treated with TNF-α with the indicated concentrations for 24 h. D: Western blot image of IRF1 ... cook hearing st joseph moWebMay 1, 2024 · Following immunoprecipitation with anti-FLAG beads, western blots were performed using the anti-pT/S antibody and re-probed with anti-FLAG to determine total IRF1 protein, and a representative blot is shown. The ratio phospho-IRF1 to total IRF1 was quantified by densitometry, and data from three independent experiments are shown. cook hearing cedar park