P-type atpase是什么
WebP-type ATPases catalyze the selective active transport of ions like H+, Na+, K+, Ca2+, Zn2+, and Cu2+ across diverse biological membrane systems. Many members of the P-type ATPase protein family, such as the Na+,K+-, H+,K+-, Ca2+-, and H+-ATPases, are involved in the development of pathophysiological conditions or provide critical function to ...
P-type atpase是什么
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WebSep 30, 2015 · Biochemical analyses of ATPase activity in yeast microsomal fractions confirmed that AtHMA1 is activated by multiple metal ions (zinc, copper, cadmium, and cobalt) and is capable of the transport of calcium, consistent with the presence of the thapsigargin-sensitive stalk segment characteristic for SERCA (sarcoplasmic/ER Ca 2+ … WebJul 9, 2009 · The unique status of this P-type ATPase is further underlined by the presence of two additional subunits, namely KdpF (3 kDa) and KdpC (20 kDa). Whereas the former is thought to be of structural importance for the integrity of the enzyme complex, the latter is most likely involved in catalysis. In this review, these rather unique features of ...
WebFunction of P-ATPase is to transport a variety of different compounds, like ions and phospholipids, across a membrane using ATP hydrolysis for energy. There are many different classes of P-ATPases, which transports a specific type of ion. P-ATPases may be composed of one or two polypeptides, and can usually take two main conformations, E1 … WebP-type ATPases form a large superfamily of cation and lipid pumps. They are remarkably …
WebSep 25, 2024 · Until recently, P-type ATPases were thought to be exclusively cation or lipid pumps. Together with the report that the P5B-ATPase ATP13A2 transports polyamines , our study reveals that P-type ATPases mediate transport of unexpectedly diverse substrates. Although the T domains of all P-type ATPases display a similar overall arrangement of … WebMay 27, 2014 · Mutations in ATP13A2 lead to Kufor-Rakeb syndrome, a parkinsonism with dementia. ATP13A2 belongs to the P-type transport ATPases, a large family of primary active transporters that exert vital cellular functions. However, the cellular function and transported substrate of ATP13A2 remain unknown. To discuss the role of ATP13A2 in …
WebJul 8, 2016 · P4-ATPases comprise a family of P-type ATPases that actively transport or flip phospholipids across cell membranes. This generates and maintains membrane lipid asymmetry, a property essential for a wide variety of cellular processes such as vesicle budding and trafficking, cell signaling, blood coagulation, apoptosis, bile and cholesterol …
WebP-type ATPases: These all form phosphorylated intermediates in the pump mechanism, … ebay instant american ginseng teaWebApr 22, 2024 · Vacuolar type H + ATPase or V type ATPase is one of the four types of ATPases. It is a membrane protein complex which has a size of 1 MDa. It is a membrane protein complex which has a size of 1 MDa. It consists of two main domains as V 0 domain and V 1 domain, having at least thirteen subunits. ebay instant cameraWebP-type ATPases form a large superfamily of cation and lipid pumps. They are remarkably … compare car insurance money saving expertWebThe P-type ATPase copper-transporting ATPase 1 (ATP7A) is a major component of the … compare car insurance between californiaWeb三磷酸腺苷合酶或ATP合酶,三磷酸腺苷酶(ATPase)的一种,在这里并特指F类 … ebay instant offer delcineWebAug 24, 2024 · KdpB is a 7-TM P-type ATPase. Like all other P-type ATPases, KdpB alternates between outward- and inward-open conformations in the so-called Post-Albers cycle, which features states E1 and E2, and ... ebay instant offer acceptWebAug 1, 2011 · Introduction. P-type ATPases are a large family of integral membrane transporters that are of vital importance in all kingdoms of life. In eponymous distinction from the other main classes of transport ATPase – the F 0 F 1 (F-), the vacuolar (V-) and the ATP-binding cassette (ABC-) type – the P-type ATPases form a phosphorylated (P ... compare car insurance perth woolworths