Ets homologous factor
WebAnalysis of three SNPs at the CAT and EHF gene located within the region of maximum linkage showed that T1667T and C (-262)T markers of the CAT gene are strongly associated with the disease [12]. In the process of identifying senescence-associated genes, we found significant suppression of the ets homologous factor (EHF) in cancer cells in … Web11 rows · In this scenario, ETS homologous factor (EHF), a molecule of the epithelium-specific subfamily ...
Ets homologous factor
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WebApr 28, 2024 · ETS is one of the largest evolutionarily conserved transcription factor families, with a unifying feature of a conserved ETS DNA-binding domain . A subset of the ETS family also contains a second... October 2024 marked the 20th anniversary of Nature Reviews Cancer.This … WebSep 6, 2024 · One of these, at chromosome 11p13, is an intergenic region between Ets homologous factor (EHF) and Apaf-1 interacting protein (APIP). Our goal was to determine the functional significance of this region, which being intergenic is probably regulatory. To identify cis-acting elements, we used DNase-seq and H3K4me1 and H3K27Ac ChIP-seq …
WebMar 2, 2024 · Abstract Background Ets homologous factor (EHF) is a member of the epithelial-specific Ets (ESE) transcription factors. EHF is specifically expressed in epithelial tissues, however its role in development and epithelial homeostasis is largely uncharacterized. WebFeb 18, 2024 · The ETS (E26 transformation-specific or erythroblast transformation specific) homologous factor, EHF, is an emerging epithelium-specific transcription factor that plays a role in many human cancers [1].
WebFeb 18, 2024 · EHF (ETS homology factor) is a transcription factor that is generally expressed in epithelial tissue and has been shown to play a role in a variety of human … WebETS homologous factor (EHF) plays a critical function in epithelial cell differentiation and proliferation. However, the roles of EHF in cancer remain largely unknown. In the present study, we investigated the expression levels, precise function and mechanism of EHF in colorectal carcinoma (CRC).
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WebETS transcription factor family. Structure of Ets-1 DNA binding autoinhibition. [1] In the field of molecular biology, the ETS ( E26 transformation-specific [2] or E-twenty-six. (Erythroblast Transformation Specific) [3]) family is one of the largest families of transcription factors and is unique to animals. There are 29 genes in humans, 28 in ... barhasingheWebApproximately 50% of prostate cancers are associated with gene fusions of the androgen-regulated gene TMPRSS2 to the oncogenic erythroblast transformation-specific (ETS) transcription factor ERG. The three-dimensional proximity of TMPRSS2 and ERG genes, in combination with DNA breaks, facilitates the formation of TMPRSS2-ERG gene fusions. suzuka kodomo clinicWebtransformation specific) homologous factor, EHF, is an emerging epithelium-specific transcription factor that plays a role in many human cancers [1]. All ETS family members … suzukaku gaWebJun 28, 2024 · The Ets family of transcription factors regulates a wide range of developmental processes, and many members have been implicated cancer. For example, Ets homologous factor (EHF), an Ets factor expressed solely in epithelia, has been associated with the progression of various cancers, but investigations into its … barhasegawaWebNov 20, 2014 · Ets homologous factor (EHF) is an Ets family transcription factor expressed in many epithelial cell types including those lining the respiratory system. Disruption of the airway epithelium is central to many lung diseases, and a network of transcription factors coordinates its normal function. EHF can act as a transcriptional … barhaspatya shastraWebETS homologous factor is a protein that in humans is encoded by the EHF gene. This gene encodes a protein that belongs to an ETS transcription factor subfamily characterized by epithelial-specific expression (ESEs). The encoded protein acts as a transcriptional repressor and may be associated with asthma susceptibility. suzukake no kaiWebMar 29, 2024 · Gene ID: 26298, updated on 8-Dec-2024 Summary This gene encodes a protein that belongs to an ETS transcription factor subfamily characterized by epithelial … bar hasuta