웹2024년 8월 4일 · The basic leucine zipper ATF-like transcription factor (BATF)/JUN/interferon regulatory factor 4 (IRF4) complex serves critical functions in the immune response. This … 웹Given that STAT3 can physically bind to c-JUN (68), it is reasonable to hypothesize that STAT3 can be recruited by BATF- JUN-IRF4 complexes via STAT3-JUN interactions …

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웹2012년 10월 25일 · Moreover, BATF-JUN family protein complexes cooperate with IRF4 in binding to AICEs in pre-activated CD4(+) T cells stimulated with IL-21 and in T(H)17 … 웹Activator protein-1 (AP-1) is a transcription factor that consists of either a Jun-Jun homodimer or a Jun-Fos heterodimer. AP-1 regulates the expression of multiple genes essential for cell proliferation, differentiation and apoptosis. Numerous reports suggest that AP-1 plays an important role in va … fast cat ryde timetable

BATF-JUN is critical for IRF4-mediated transcription in T cells.

웹20시간 전 · c-Jun jest protein koji je kod ljudi kodiran genom JUN sa hromosoma 1. c-Jun, u kombinaciji sa c-Fos, formira AP-1 transkripcijski faktor za rani odgovor, Prvo je identificiran kao Fos-vezujući protein p39 i tek kasnije ponovo otkriven kao proizvod gena JUN. c-jun je bio prvootkriveni onkogeni transkripcijski faktor. The proto-oncogene c-Jun je ćelijski homolog … 웹During chronic stimulation, CD8+ T cells acquire an exhausted phenotype characterized by expression of inhibitory receptors, loss of effector function, and metabolic impairments. … 웹2024년 3월 21일 · Background. Marfan syndrome (MFS) is a clinically heterogeneous hereditary connective tissue disorder. Severe cardiovascular manifestations (i.e., aortic aneurysm and dissection) are the most life-threatening complications. Most of the cases are caused by mutations, a minor group of which are copy number variations (CNV), in the … freight forwarding market size 2022