Atdili
WebJun 13, 2016 · Evidence indicates that the polymorphisms in bile salt export pump (BSEP, encoded by ABCB11) may play an important role in the development of anti-tuberculosis … WebApr 20, 2024 · Therefore, in order to terminate TB infection, ATDILI prevention is an unavoidable concern. Doubtlessly, reliable and specific biomarkers for ATDILI …
Atdili
Did you know?
WebJul 1, 2016 · A better understanding of risk factors of ATDILI may assist in the prevention and management of this crucial adverse drug reaction.5, 6 Elderly, Asian, malnutrition, alcoholism, chronic hepatitis B and C infections, AIDS, pregnancy, coadministration of hepatotoxic agents, abnormal baseline liver function, and genetic factors have been … WebDespite being highly effective, anti-tuberculosis (TB) drugs often induce adverse liver injury, anti-TB drug-induced liver injury (ATDILI), leading to... DOAJ is a unique and extensive index of diverse open access journals from around the world, driven by a growing community, committed to ensuring quality content is freely available online for ...
WebAntituberculosis drug-induced liver injury (ATDILI) is increasing globally and, hence, it is crucial to predict its risk in the clinical management of antituberculosis therapy. As a major antioxidant, superoxide dismutase (SOD) is mainly responsible for providing defence against oxidative stress, which is involved in ATDILI. WebObjectives: This study aimed to investigate whether mitochondrial DNA (mtDNA) content, an index of mitochondrial dysfunction, was associated with clinical parameters indicating …
WebApr 1, 2024 · Objectives. Anti-tuberculosis drug-induced liver injury (ATDILI) is a common and sometimes severe adverse drug reaction (ADR). This study was conducted to investigate the relationship between polymorphisms of two genes, cytochrome P450 oxidoreductase (POR) and peroxisome proliferator-activated receptor α (PPARα), and … WebBackground and aims: Anti-tuberculosis drugs remain as an important cause of drug-induced liver injury (DILI) worldwide. Adverse drug reactions reduce the effectiveness of …
WebMar 27, 2024 · Abstract Despite being relatively rare, anti-tuberculosis drug-induced liver injury (ATDILI) is a leading cause of acute liver failure and a major reason for treatment …
WebFeb 1, 2024 · The patients were followed up monthly to monitor the development of ATDILI. The C allele and the CA genotype of rs7852860 were significantly associated with an elevated risk for ATDILI (p = .006 and 0.005, respectively), which was consistent with the results in the dominant and additive models. No allele, genotype, or genetic model of the … jesué pinharanda gomesWebMar 27, 2024 · Despite being relatively rare, anti-tuberculosis drug-induced liver injury (ATDILI) is a leading cause of acute liver failure and a major reason for treatment … jesue什么意思WebApr 18, 2024 · Anti-tuberculosis drugs remain as an important cause of drug-induced liver injury (DILI) worldwide. Adverse drug reactions reduce the effectiveness of treatment. … jesu endzeitredeWeb万方 掌桥科研 维普网 万方医学 知网 查看更多 维普网 钛学术 《中国防痨杂志》官网 (全网免费下载) kns.cnki.net 《中国防痨杂志》官网 钛学术 (全网免费下载) lampbudgetWebAntituberculosis drug-induced liver injury (ATDILI) is the common adverse reaction of antituberculosis drugs. Glutathione S-transferases (GSTs), which are phase II metabolizing enzymes for ... lamp b\\u0026mWebG.R. Fleisher et al. Intramuscular versus oral antibiotic therapy for the prevention of meningitis and other bacterial sequelae in young febrile children at risk for occult bacteremia lamp btsWebBACKGROUND AND OBJECTIVE: A number of studies have evaluated the association between cytochrome P450 2E1 (CYP2E1) RsaI/PstI polymorphism and the risk of anti-tuberculosis drug-induced liver injury (ATDILI). However, the results were inconsistent. We conducted a meta-analysis to clarify the role of this polymorphism in ATDILI. lamp buffet